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10 best startup cities in South America

Active founder communities, accelerators, and a critical mass of investors.

Ranked by climate, cost of living, language access, safety, and lifestyle fit. Personalize this →

  1. #1

    Florianópolis, Brazil

    78
    match

    Brazilian surf island that quietly became a remote-work magnet. 40+ beaches, easygoing pace.

  2. #2

    Santiago, Chile

    78
    match

    Andes on the horizon, vineyards in the suburbs, and the highest standard of living in South America.

  3. #3

    São Paulo, Brazil

    77
    match

    Latin America's biggest city. Concrete jungle, world-class food, the continent's startup engine.

  4. #4

    Bogotá, Colombia

    77
    match

    Andean capital at 2,600m. Cool, cloudy, intellectual, and Colombia's economic engine.

Startup cities in other regions

Other rankings in South America